Don’t Use CCLTDs as Vanity Domains
Don’t use a country specific top level domain (e.g. .it) as this will tell Google that the site is primarily for that country.
.eu and .asia Domains are Global
.eu and and .asia domains are treated as generic TLDS.
Set Geographic Regions for non-ccTLDs on CDNs
If you have a generic top-level domain which doesn’t specify a country, and you use a CDN, you should make sure you have the geographic settings applied in Search Console.
All Top Level Domains Are Equal
Google doesn’t treat any top-level domains differently. So a .com is treated no differently to a .info.